Stress effects tonic – stimulant
Conditions of nervous exhaustion, nervous weakness, fatigue, and depression; insomnia; nervous headaches; lethargy; general nervous fatigue, physical fatigue; inability to concentrate.
vC-15 forte is enriched with 0.5% ascorbic acid; this addition renders it a potent activator of cellular metabolism – acting both at the cellular, as well as humoral levels. Aralia quinquefolia (Ginseng) is a well documented antifatigue and anti-stress herb. In combinations with the other ingredients in this specialty, Ginseng aids in providing full tonification and vitalization of the entire organism.
v-C15 forte is truly a “tonic” for the entire system, as will become clear from the actions of the individual constituents below:
Mode of action
Panax Ginseng: The main pharmacological constituents of Ginseng include: glucosides, panax acid and the volatile oil Panacen, vitamins B1 and B2, estrogenic components, the sympathiomimetic gensonoside constituent, and a remarkably high concentration of the mineral, sulphur (approx. 0.15%). The tonic effect may be explained by the synergistic interaction of these individual constituents. However, the revitalizing actions may also be contributed to the content of vitamin B1 (thyamine) and B2 (riboflavin). In combination with the ascorbic acid in this formulation, these substances act on the most important systems involved in the body’s adaption during stressful situations. An adequate supply of these vitamins assists the organism to adapt and develop resistance to stress.
- Thyamine: Acts on the cells of the body which have an elevated requirement for carbohydrates (nerve cells), cells with a metabolism based mainly on the substrate pyruvic acid (cardiac muscle cells), and nervous tissues that utilize acetylcholine as a neurotransmitter. Thyamine inhibits the cholinesterase enzyme and increases the effect of acetylcholine. This is very important, as cholinesterase causes the degradation of acetylcholine. The cholinesterase enzyme is very quick acting, and its effect on acetylcholine is of short duration.
- Riboflavin: May be found endogenously, in large amounts in the retina, and most likely plays a role in visual acuity. An adequate supply of riboflavin in the retina is important, as it has been noted that during stressful situations, in conditions of deficiency, there is a decrease in visual acuity and irritation of the eyes. In addition, riboflavin functions as a cofactor to different enzymes, such as cytochrome dehydrogenase, amino oxidases and the enzymes which are responsible for cellular respiration.
- Ginseng’s high sulphur content undoubtedly is a positive factor in energy exchange of the cells. Sulphur is a component of amino acid, such as the essential amino acid, cysteine. This amino acid functions as the main carrier for sulphur in several proteins, including lactalbumin. Cysteine as an intermediate catalyst, participates in a reducing system of great importance to cellular energy exchange. As a catalyst cysteine functions to absorb and eventually release hydrogen liberated during the cellular process of dehydrogenation, and thus, allows for a gradual release of energy.
- L-ascorbic acid (vitamin C) is an activator of cellular metabolism – of both the cellular and humoral processes. Ascorbic acid is a physiological tonic, which acts to tonify and vitalize the system. Ascorbic acid functions as an electron reducer; in cellular metabolism it acts to transfer hydrogen and electrons in a reversible process. Vitamin C plays a definitive role in the synthesis of steroid hormones. This renders vitamin C of great importance during stressful situations.
During situations of stress, there is an increase in the production of steroid hormones; the vitamin C level in the adrenal cortex falls and this inadequacy causes a reduction in hormone synthesis. This does not allow for the process of adaption.